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1

Product development issues for PEGylated proteins

Payne, Robert W., Murphy, Brian M., Manning, Mark Cornell

Journal:

Pharmaceutical Development and Technology

Year:

2011

Language:

english

File:

PDF, 807 KB

english, 2011

2

Characterization of amorphous solids with weak glass transitions using high ramp rate differential scanning calorimetry

Derrick S. Katayama, John F. Carpenter, Mark Cornell Manning, Theodore W. Randolph, Peter Setlow, Kevin P. Menard

Journal:

Journal of Pharmaceutical Sciences

Year:

2008

Language:

english

File:

PDF, 558 KB

english, 2008

3

Stability of Protein Pharmaceuticals: An Update

Mark Cornell Manning, Danny K. Chou, Brian M. Murphy, Robert W. Payne, Derrick S. Katayama

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 633 KB

english, 2010

4

Characterization of Protein Higher Order Structure Using Vibrational Circular Dichroism Spectroscopy

P. Nagarkar, Radhika, M. Murphy, Brian, Yu, Xiaotong, Cornell Manning, Mark, A. Al-Azzam, Wasfi

Journal:

Current Pharmaceutical Biotechnology

Year:

2013

Language:

english

File:

PDF, 388 KB

english, 2013

5

Role of Buffers in Protein Formulations

Zbacnik, Teddy J., Holcomb, Ryan E., Katayama, Derrick S., Murphy, Brian M., Payne, Robert W., Coccaro, Richard C., Evans, Gabriel J., Matsuura, James E., Henry, Charles S., Manning, Mark Cornell

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 2.63 MB

english, 2016

6

Second virial coefficient determination of a therapeutic peptide by self-interaction chromatography

Robert W. Payne, Rajiv Nayar, Ralph Tarantino, Sam Del Terzo, John Moschera, Jie Di, David Heilman, Brian Bray, Mark Cornell Manning, Charles S. Henry

Journal:

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

7

Effects of Tween 20® and Tween 80® on the stability of Albutropin during agitation

Danny K. Chou, Rajesh Krishnamurthy, Theodore W. Randolph, John F. Carpenter, Mark Cornell Manning

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 235 KB

english, 2005

8

Noninvasive determination of protein conformation in the solid state using near infrared (NIR) spectroscopy

Shujun Bai, Rajiv Nayar, John F. Carpenter, Mark Cornell Manning

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 145 KB

english, 2005

9

Solution behavior of a novel type 1 interferon, interferon-τ

Derrick. S. Katayama, Rajiv Nayar, Danny K. Chou, Jackie Campos, Julianne Cooper, David G. Vander Velde, Lorelie Villarete, C.P. Liu, Mark Cornell Manning

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

10

Effect of buffer species on the thermally induced aggregation of interferon-tau

Derrick S. Katayama, Rajiv Nayar, Danny K. Chou, Joseph J. Valente, Julianne Cooper, Charles S. Henry, David G. Vander Velde, Lorelie Villarete, C.P. Liu, Mark Cornell Manning

Journal:

Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 320 KB

english, 2006

11

Mixing properties of lyophilized protein systems: A spectroscopic and calorimetric study

Derrick S. Katayama, John F. Carpenter, Kevin P. Menard, Mark Cornell Manning, Theodore W. Randolph

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 238 KB

english, 2009

12

Aggregation of recombinant human botulinum protein antigen serotype c in varying solution conditions: Implications of conformational stability for aggregation kinetics

Shujun Bai, Mark Cornell Manning, Theodore W. Randolph, John F. Carpenter

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 460 KB

english, 2011

13

Structure, stability, and mobility of a lyophilized IgG1 monoclonal antibody as determined using second-derivative infrared spectroscopy

Brian M. Murphy, Ning Zhang, Robert W. Payne, Janice M. Davis, Ahmad M. Abdul-fattah, James E. Matsuura, Alan C. Herman, Mark Cornell Manning

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 453 KB

english, 2012

14

Feasibility of Tissue Plasminogen Activator Formulated for Pulmonary Delivery

John S. Dunn, Rajiv Nayar, Jackie Campos, Brooks M. Hybertson, Yue Zhou, Mark Cornell Manning, John E. Repine, Kathleen A. Stringer

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 453 KB

english, 2005

15

Multivariate Analysis of the Sequence Dependence of Asparagine Deamidation Rates in Peptides

Andrew A. Kosky, Vasumathi Dharmavaram, Gayathri Ratnaswamy, Mark Cornell Manning

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 365 KB

english, 2009

16

Comparability of protein therapeutics: Quantitative comparison of second-derivative amide I infrared spectra

Jennifer D'antonio, Brian M. Murphy, Mark Cornell Manning, Wasfi A. Al-azzam

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 312 KB

english, 2012

17

Physical stability of albinterferon-α2b in aqueous solution: Effects of conformational stability and colloidal stability on aggregation

Danny K. Chou, Rajesh Krishnamurthy, Mark Cornell Manning, Theodore W. Randolph, John F. Carpenter

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 986 KB

english, 2012

18

Impact of bulking agents on the stability of a lyophilized monoclonal antibody

Jeffrey D. Meyer, Rajiv Nayar, Mark Cornell Manning

Journal:

European Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 919 KB

english, 2009

19

Use of infrared spectroscopy to monitor protein structure and stability

Manning, Mark Cornell

Journal:

Expert Review of Proteomics

Year:

2005

Language:

english

File:

PDF, 242 KB

english, 2005

20

Aggregation of human serum albumin during a thermal viral inactivation step

Jen-Jen Lin, Jeffrey D. Meyer, John F. Carpenter, Mark Cornell Manning

Journal:

International Journal of Biological Macromolecules

Year:

2009

Language:

english

File:

PDF, 530 KB

english, 2009

21

Murphy B, Zhang N, Payne R, Davis J, Abdul-Fattah A, Matsuura J, Herman A, Manning M. 2012. Structure, stability, and mobility of a lyophilized IgG1 monoclonal antibody as determined using second-derivative infrared spectroscopy. J Pharm Sci 101:81–91.

Brian M. Murphy, Ning Zhang, Robert W. Payne, Janice M. Davis, Ahmad M. Abdul-Fattah, James E. Matsuura, Alan C. Herman, Mark Cornell Manning

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 343 KB

english, 2012

22

Effects of solution conditions on methionine oxidation in albinterferon alfa-2b and the role of oxidation in its conformation and aggregation

Chou, Danny K., Krishnamurthy, Rajesh, Manning, Mark Cornell, Randolph, Theodore W., Carpenter, John F.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 460 KB

english, 2013

23

Second Virial Coefficient Studies of Cosolvent-Induced Protein Self-Interaction

Valente, Joseph J., Verma, Kusum S., Manning, Mark Cornell, William Wilson, W., Henry, Charles S.

Journal:

Biophysical Journal

Year:

2005

Language:

english

File:

PDF, 123 KB

english, 2005

24

Flow imaging: Moving toward best practices for subvisible particle quantitation in protein products

Wilson, Glenn A., Manning, Mark Cornell

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

25

Stability of lyophilized sucrose formulations of an IgG1: subvisible particle formation

Davis, Janice M., Zhang, Ning, Payne, Robert W., Murphy, Brian M., Abdul-Fattah, Ahmad M., Matsuura, James E., Herman, Alan C., Manning, Mark Cornell

Journal:

Pharmaceutical Development and Technology

Year:

2013

Language:

english

File:

PDF, 999 KB

english, 2013

26

Ability of Two Natural Products, Nootkatone and Carvacrol, to Suppress Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) in a Lyme Disease Endemic Area of New Jersey

Dolan, Marc C., Jordan, Robert A., Schulze, Terry L., Schulze, Christopher J., Manning, Mark Cornell, Ruffolo, Daniel, Schmidt, Jason P., Piesman, Joseph, Karchesy, Joseph J.

Journal:

Journal of Economic Entomology

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

27

Stability of lyophilized teriparatide, PTH(1-34), after reconstitution

Merutka, Gene, Murphy, Brian M., Payne, Robert W., Wilson, Glenn A., Matsuura, James E., Henry, Charles S., Manning, Mark Cornell

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

28

Comparability of Higher Order Structure in Proteins: Chemometric Analysis of Second-Derivative Amide I Fourier Transform Infrared Spectra

Stockdale, Gregory, Murphy, Brian M., D'Antonio, Jennifer, Manning, Mark Cornell, Al-Azzam, Wasfi

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 946 KB

english, 2015

29

High throughput detection of deamidation using S-(5′-adenosyl)- l -homocysteine hydrolase and a fluorogenic reagent

Murphy, Brian M., Ozumerzifon, Tarik J., Henry, Charles S., Manning, Mark Cornell

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 909 KB

english, 2018

30

The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication

Man, Adrian, Slevin, Mark, Petcu, Eugen, Fraefel, Cornel

Journal:

Scientific Reports

Year:

2019

File:

PDF, 1.29 MB

2019

31

The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication

Man, Adrian, Slevin, Mark, Petcu, Eugen, Fraefel, Cornel

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.29 MB

english, 2019

32

Outcomes of patients with multiple myeloma refractory to CD38-targeted monoclonal antibody therapy

Gandhi, Ujjawal H., Cornell, Robert F., Lakshman, Arjun, Gahvari, Zhubin J., McGehee, Elizabeth, Jagosky, Megan H., Gupta, Ridhi, Varnado, William, Fiala, Mark A., Chhabra, Saurabh, Malek, Ehsan, Mans

Journal:

Year:

2019

File:

PDF, 783 KB

2019

33

Shape Characterization of Subvisible Particles Using Dynamic Imaging Analysis

Mathaes, Roman, Manning, Mark Cornell, Winter, Gerhard, Engert, Julia, Wilson, Glenn A.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 788 KB

english, 2019

34

Shape Characterization of Subvisible Particles Using Dynamic Imaging Analysis

Mathaes, Roman, Manning, Mark Cornell, Winter, Gerhard, Engert, Julia, Wilson, Glenn A.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

File:

PDF, 788 KB

2019

35

A Chemometric Approach Toward Predicting the Relative Aggregation Propensity: Aβ(1-42)

Zbacnik, Nathaniel J., Henry, Charles S., Manning, Mark Cornell

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.51 MB

english, 2019

36

A Chemometric Approach Toward Predicting the Relative Aggregation Propensity: Aβ(1-42)

Zbacnik, Nathaniel J., Henry, Charles S., Manning, Mark Cornell

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

File:

PDF, 1.51 MB

2019